A Look at LEMS

Mary Ann, living with LEMS

Now Available!

A Look at LEMS

Learn. Engage. Meet. Share.

An on-demand educational session to help you find clear and simple information about Lambert-Eaton myasthenic syndrome (LEMS).

Learn more, be empowered, and find the best path forward for you.

Meet your moderator, Amy Grover, Director of Patient Advocacy at Catalyst Pharmaceuticals. Amy works with the LEMS community and advocacy groups to help provide support, tools, and resources that are unique to each patient’s journey.

Learn about LEMS and an FDA-approved therapy from neuromuscular specialist Dr. David P. Randall, Director of Neuromuscular Neurology for Advocate Medical Group.

Meet Mary Ann and hear about her journey to a LEMS diagnosis.

Learn about Catalyst Pathways, a free, personalized program that offers one-on-one support throughout your treatment journey presented by Maria Pandolfo, Vice President of Patient Services at Catalyst Pharmaceuticals.

Catalyst Pharmaceuticals
355 Alhambra Circle, Suite 801, Coral Gables, FL 33134
Tel: 1-844-347-3277 (1-844-FIRDAPSE) | catalystpharma.com
Contact Catalyst Pharmaceuticals

FIRDAPSE^® is a registered trademark of SERB
© 2021 Catalyst Pharmaceuticals, Inc. All Rights Reserved. 21LEM0440b(3). November 2021
Privacy Policy

What is FIRDAPSE^®?

FIRDAPSE is a prescription medicine used to treat adults 17 years of age or older with Lambert-Eaton myasthenic syndrome (LEMS). The safety and efficacy of FIRDAPSE in patients under the age of 17 has not been established.

IMPORTANT SAFETY INFORMATION

What is the most important information you should know about FIRDAPSE?

FIRDAPSE can cause seizures.
- You could have a seizure even if you never had a seizure before.
- Do not take FIRDAPSE if you have ever had a seizure.

Stop taking FIRDAPSE and call your doctor right away if you have a seizure while taking FIRDAPSE.

Do not take FIRDAPSE if you:

have ever had a seizure
are allergic to amifampridine phosphate, or another aminopyridine

Before you take FIRDAPSE, tell your doctor about all of your medical conditions, including if you:

are taking another aminopyridine, such as compounded 3,4-diaminopyridine (3,4-DAP)
have had a seizure
have kidney problems
have liver problems
are pregnant or plan to become pregnant. It is not known if FIRDAPSE will harm your unborn baby. You and your doctor will decide if you should take FIRDAPSE while you are pregnant.
There is a registry for women who become pregnant during treatment with FIRDAPSE. The purpose of this registry is to collect information about your health and your baby’s health. Contact the registry as soon as you learn that you are pregnant, or ask your healthcare provider to contact for you by calling 855-212-5856 (toll free), contacting the Fax number 877-867-1874 (toll free), emailing the Pregnancy Coordinating Center at firdapsepregnancyregistry@ubc.com, or visiting the study website www.firdapsepregnancystudy.com.
are breastfeeding or plan to breastfeed. It is not known if FIRDAPSE passes into your breast milk. Talk to your doctor about the best way to feed your baby while taking FIRDAPSE.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should you take FIRDAPSE?

Take FIRDAPSE exactly as your doctor tells you to take it. Do not change your dose of FIRDAPSE.
Do not take more than 2 tablets of FIRDAPSE at one time or more than 8 tablets of FIRDAPSE in a 24-hour period.
FIRDAPSE can be taken with or without food.
If you miss a dose of FIRDAPSE, skip that dose and take your next dose at your next scheduled dose time. Do not double your dose to make up the missed dose.
Do not take FIRDAPSE together with other medicines known to increase the risk of seizures.
If you take too much FIRDAPSE, call your doctor or go to the nearest hospital emergency room right away.

What are the possible side effects of FIRDAPSE?

FIRDAPSE may cause serious side effects, including:

Seizures. See “What is the most important information you should know about FIRDAPSE?”
Serious allergic reactions, such as anaphylaxis. FIRDAPSE can cause serious allergic reactions. Stop taking FIRDAPSE and call your doctor right away or get emergency medical help if you have:
- shortness of breath or trouble breathing
- swelling of your throat or tongue
- hives
The most common side effects of FIRDAPSE include:

tingling around the mouth, tongue, face, fingers, toes, and other body parts
upper respiratory infection
stomach pain
nausea
diarrhea
headache
increased liver enzymes
back pain
high blood pressure
muscle spasms

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of FIRDAPSE.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should you store FIRDAPSE?

Store FIRDAPSE at 68ºF to 77ºF (20ºC to 25ºC).
Safely throw away FIRDAPSE that is out of date or no longer needed.

Keep FIRDAPSE and all medicines out of the reach of children.

If you would like more information, ask your doctor or pharmacist for additional information about FIRDAPSE.

The active ingredient in FIRDAPSE is amifampridine phosphate. Inactive ingredients are calcium stearate, colloidal silicon dioxide, and microcrystalline cellulose.

Please see full at Prescribing Information for additional Important Safety Information.